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WEBBig pharma eyes China ‘at forefront of GLP-1 revolution’. Two leading glucagon-like peptide-1 (GLP-1) receptor agonists for obesity and type 2 diabetes – Novo Nordisk A/S’s semaglutide (Wegovy/Ozempic) and Eli Lilly and Co.’s... More in BioWorld Asia. Daily news and analysis of the global biotechnology, pharmaceutical and medical ...
BioWorld MedTech: The Daily Medical Technology News Source
WEBBioWorld Premium. Enjoy extended coverage for the most complete market view with BioWorld, BioWorld MedTech, and BioWorld Asia in a single, easy to access subscription. Daily news and analysis of the medical technology industry. In-depth coverage of business, financing, regulation, science, innovation, device approvals, clinical trials and more.
Hainan Simcere Pharmaceutical discloses CBL-B inhibitors
WEBAug. 14, 2024. No Comments. Hainan Simcere Pharmaceutical Co. Ltd. has patented E3 ubiquitin-protein ligase CBL-B (CBLB) inhibitors reported to be useful for the treatment of cancer and autoimmune diseases. BioWorld Science Cancer Patents.
Drugs - BioWorld
WEBApr 26, 2024 · Drugs to Watch 2024: A baker’s dozen of potential blockbusters and gamechangers. The 2024 edition of Clarivate’s Drugs to Watch features 13 drugs that highlight an inflection point where amazing, merging tech is finally paying off with ADCs and CRISPR/Cas9 and bispecifics, Matthew Arnold, principal …
Structural study gives insights into influenza virus species jumps
WEBAug 20, 2024 · Structural study gives insights into influenza virus species jumps. Aug. 20, 2024. By Anette Breindl. “There are hundreds of strains of bird flu, and most of them don’t infect humans, or even mammals,” Stephen Cusack told BioWorld. “There are two main reasons for that.”. To be able to cause an infection, a virus “has to be able to ...
Getinge to acquire Paragonix for $477M | BioWorld
WEBAug 23, 2024 · Getinge AB agreed to acquire Paragonix Technologies Inc. for $477 million, including upfront and earn out payments. The deal marks Getinge’s entry into the global organ preservation and transportation market, a rapidly advancing field driven by rising transplant volumes, technological innovations and evolving clinical practices.
Cancer - BioWorld
WEBSep 13, 2024 · MBX joins Bicara and Zenas in trio of IPO pricings. Three biopharmas debuted on Nasdaq Sept. 13, raising a combined $703 million for two Massachusetts-based companies focused on bifunctional antibodies for autoimmune diseases and cancer, and one Midwestern firm developing peptide therapies for endocrine and metabolic disorders.
China - BioWorld
WEB5 days ago · Sep. 17, 2024. By Marian (YoonJee) Chu. No Comments. Chinese pharmaceutical and biotech companies are leading development of glucagon-like peptide-1 receptor agonists as Novo Nordisk A/S and Eli Lilly and Co. edge closer to launching blockbuster therapies in China. At the heart of the GLP-1 boom is a nationwide obesity problem driven by a ...
ASP-3082, a PROTAC that selectively degrades KRAS G12D
WEBOct 27, 2022 · Kirsten rat sarcoma viral oncogene (KRAS) is one of the GTPases from the RAS family activating signaling pathways that regulate cell functions. KRAS mutation of glycine to aspartate at position 12 (G12D) is a common mutation in pancreatic ductal adenocarcinoma, colorectal cancer, lung adenocarcinoma and other solid tumors. ASP-3082 is a proteolysis targeting chimera (PROTAC) under development ...
Proline links gut microbiome to depression - BioWorld
WEBMay 9, 2022 · Using a multi-omics approach, scientists in Spain have now identified high levels of proline as a metabolite that is directly linked to depression severity, and shown that variations in levels of circulating proline are dependent on microbiome composition. When mice are given a fecal microbiota transplant from humans with depression, the mice ...