This is the second of three straight home games for Arizona. The Cardinals are scheduled to host the Washington Commanders in NFL Week 4 on Sept. 29. Arizona is coming off a 41-10 win over the Los Angeles Rams in NFL Week 2.

The Cardinals are coming off a 41-10 rout of the Los Angeles Rams last week, where Kyler Murray finished with 266 passing yards and three touchdowns. Containing Murray and rookie receiver Marvin Harrison Jr., who had 130 receiving yards and two touchdowns on four catches in that same game, will be a challenge for the Lions defense.